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Therapeutic Management of Glaucoma

Swank Pharm®

Introduction
•Glaucoma is an eye disease in which the optic nerve is damaged in a characteristic pattern.
•This can permanently damage vision in the affected eye(s) and lead to blindness if left untreated.
•It is normally associated with increased fluid pressure in the eye (aqueous humour).

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Pathophysiology and Etiology of Glaucoma
•Of the several causes for glaucoma, ocular hypertension (increased pressure within the eye) is the most important cause in most glaucomas, but in some populations, only 50% of people actually have elevated ocular pressure.
•Intra-ocular pressure rises when there is an imbalance between production and drainage of aqueous humour in the eye.

Risk factors
•Old age
•Family history of glaucoma
•Thinner central corneal thickness
•Raised intra-ocular pressure is an important risk factor for glaucoma

Classification of glaucoma
Glaucoma is classified as open-angle or angle-closure depending on the mechanism of the obstruction of drainage.

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